Strolled around a bit to find a good spot, then just stood at the gas station exit to the motorway with a Praha sign for 30 minutes. Very few cars going through the gas station, but in my opinion still the best bet going West from Brno since all cars go in the direction of Prague. Eventually got picked up by an extremely nice Slovakian/Ukrainian couple and got dropped off exactly where I wanted to go in Prague. About reaching the gas station: like the hitchhiker before me, I drove to the station with the train (two stops, S4/S41), then went along the street to the bridge under the motorway. Climbed up the steep hill next to the bridge and walked 500 m alongside the motorway (outside the railing!!) to the gas station. Not the best spot to reach, but very doable and a lot easier than I imagined after reading the other comments
Thu 2026-08-27 12:10 · 10 min wait · 148 km ⭐⭐⭐⭐⭐
48.1679, 17.0780
Very good spot for hitching with a sign in the direction of Czechia, got a ride to Brno within 10 minutes. Lots of cars with Slovak number plates but some with Czech plates too. The spot is after a crossroad, so cars don't go too fast, and they can stop at the bus station that is following afterwards. Make sure your sign is big enough since the street is very wide. Also make sure to apply sunscreen on sunny days, there is no shade whatsoever
Tue 2026-08-25 13:35 · 25 min wait · 62 km ⭐⭐⭐⭐
48.1816, 16.4448
Had a sign saying Bratislava and stood next to the motorway entrance. Most cars were leaving the motorway to go to the industrial district, but after 25 minutes I got picked up by two Serbian guys around 30 driving directly to Bratislava. The gas station isn't frequented much, I think a sign works better here than asking people filling up their tanks. Good spot to go East